Piperazine → HCID 12817060, compound

HRID 2308668Notes

Reaction equation

HRID 2308668 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:19]2[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([NH:12][CH:13]3[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[CH:13]1([NH:12][C:8]2[C:6]3[N:7]=[C:2]([N:26]4[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]4)[N:3]=[C:4]([N:19]4[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]4)[C:5]=3[N:11]=[CH:10][N:9]=2)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 12817004HCID 12817004, compound

Product 1

HCID 12817060HCID 12817060, compound

Procedure

This compound was prepared analogous to Example 123 from 2-chloro-8-cyclohexylamino-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 207°-209° C.) and piperazine.

Sources & evidence

ORD record
ord-50089fbd819b4b2ba89fa26e85f8bedf
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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