Piperazine → HCID 12817078, compound

HRID 2308674Notes

Reaction equation

HRID 2308674 reaction equation
[CH2:1]([N:8]([CH2:27][CH2:28][CH2:29][CH3:30])[C:9]1[C:14]2[N:15]=[C:16](Cl)[N:17]=[C:18]([N:19]3[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]3)[C:13]=2[N:12]=[CH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[CH2:1]([N:8]([CH2:27][CH2:28][CH2:29][CH3:30])[C:9]1[C:14]2[N:15]=[C:16]([N:31]3[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]3)[N:17]=[C:18]([N:19]3[CH2:24][CH2:23][S:22](=[O:25])[CH2:21][CH2:20]3)[C:13]=2[N:12]=[CH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 12817023HCID 12817023, compound

Product 1

HCID 12817078HCID 12817078, compound

Procedure

This compound was prepared analogous to Example 118 from 8-(N-benzyl-butylamino)-2-chloro-4-(1-oxido-thiomorpholino)-pyrimido-[5,4-d]-pyrimidine (m.p.: 153°-155° C.) and piperazine.

Sources & evidence

ORD record
ord-ae818ddc8b694798894991ae973e8850
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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