Piperazine → HCID 12817080, compound

HRID 2308675Notes

Reaction equation

HRID 2308675 reaction equation
Cl[C:2]1[N:3]=[C:4]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([N:12]([CH3:19])[C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[C:6]=2[N:7]=1.[NH:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>>[CH3:19][N:12]([C:8]1[C:6]2[N:7]=[C:2]([N:26]3[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]3)[N:3]=[C:4]([N:20]3[CH2:25][CH2:24][O:23][CH2:22][CH2:21]3)[C:5]=2[N:11]=[CH:10][N:9]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 12817026HCID 12817026, compound

Product 1

HCID 12817080HCID 12817080, compound

Procedure

This compound was prepared analogous to Example 118 from 2-chloro-8-(N-methylanilino)-4-morpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 150°-152° C.) and piperazine.

Sources & evidence

ORD record
ord-7bccb2b933374bea8d7b5e50c81f8766
Source dataset
uspto-grants-1987_09
Patent number
US04690923

Reaction notes

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