HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-chloro-N-phenylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 2-Chloropropionyl chloride | HCID 111019 | — |
| Product | 2-chloro-N-phenylpropanamide | HCID 264646 | 94.8% |
Reaction Steps
18 g of aniline are introduced dropwise into 22.6 g of 2-chloropropionyl chloride at a temperature of about 10° C., with stirring until the evolution of HCl has ended. After filtration, 31 g (yield: 84.5%) of α-chloro-α-methylacetanilide are obtained in the form of a pink powder. M.p. (inst.)=80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04690950 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-6faf5a65b2ed4d0181fcc5ef07c89e82 |
| Source note | uspto-grants-1987_09 |