HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 20187493, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Bromo-1-(3,4-dimethoxyphenyl)propan-1-one | HCID 226485 | — |
| Reactant | 4-[(4-Methylphenyl)methyl]piperidine | HCID 3375603 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20187493 | HCID 20187493 | — |
Reaction Steps
5.4 g (0.05 mol) of sodium carbonate are added to a mixture of 13.65 g (0.05 mol) of 2-bromo-3',4'-dimethoxypropiophenone and 9.46 g (0.05 mol) of 4-(4-methylbenzyl)-piperidine in 50 ml of ethanol and the mixture is heated under reflux for 3 hours. It is then evaporated to dryness and the residue is passed through a column of silica using acetone as the eluant. This gives an oil, which is used as such.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04690931 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-96a13481ddf1492cb0f4ea7207a0d47f |
| Source note | uspto-grants-1987_09 |