反应详情

To a solution of 4-benzyloxy-3-[(E)-2-phenylvinyl]indole (0.1 g) in ethanol (5 mL) was added 10% palladium-carbon powder (25 mg), and the mixture was stirred at room temperature under a hydrogen atmosphere overnight. The insoluble material was removed by filtration. The filtrate was concentrated under reduced pressure, and the residue was purified by column chromatography on aminopropylated silica gel (eluent: n-hexane/ethyl acetate=3/1) to give the title compound (70 mg).

1. customThe insoluble material was removed by filtration
2. concentrationThe filtrate was concentrated under reduced pressure
3. customthe residue was purified by column chromatography on aminopropylated silica gel (eluent: n-hexane/ethyl acetate=3/1)