4-Benzyloxy-3-[(E)-2-phenylvinyl]indole → 4-Hydroxy-3-(2-phenylethyl)indole

Participants

Reaction Steps

To a solution of 4-benzyloxy-3-[(E)-2-phenylvinyl]indole (0.1 g) in ethanol (5 mL) was added 10% palladium-carbon powder (25 mg), and the mixture was stirred at room temperature under a hydrogen atmosphere overnight. The insoluble material was removed by filtration. The filtrate was concentrated under reduced pressure, and the residue was purified by column chromatography on aminopropylated silica gel (eluent: n-hexane/ethyl acetate=3/1) to give the title compound (70 mg).

Provenance & Evidence