Sodium Hydroxide → 2-[(2-Chloro-6-hydrazinylphenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one

HRID 2308902Notes

Reaction equation

HRID 2308902 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][NH2:10])[C:4]=1[CH2:11][N:12]1[C:16](=[O:17])[C:15]([CH3:19])([CH3:18])[CH2:14][O:13]1.[OH-].[Na+]>>[Cl:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][NH2:10])[C:4]=1[CH2:11][N:12]1[C:16](=[O:17])[C:15]([CH3:19])([CH3:18])[CH2:14][O:13]1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 139349472-[(2-Chloro-6-hydrazinophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone hydrochloride

Product 1

HCID 139349462-[(2-Chloro-6-hydrazinylphenyl)methyl]-4,4-dimethyl-1,2-oxazolidin-3-one

Procedure

The free hydrazine was obtained by treating of the yellow solid with aqueous sodium hydroxide. The mixture was extracted with ethyl acetate, and the extract was concentrated under reduced pressure to yield the free hydrazine.

Workup

  1. extractionThe mixture was extracted with ethyl acetate
  2. concentrationthe extract was concentrated under reduced pressure

Sources & evidence

ORD record
ord-a865dbd9beac42ad86d62507da12d43b
Source dataset
uspto-grants-1987_09
Patent number
US04692182

Reaction notes

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