HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → [1,3]Thiazolo[5,4-b]pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-3-pyridylamine | HCID 80528 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | [1,3]Thiazolo[5,4-b]pyridin-2-amine | HCID 592050 | — |
Reaction Steps
The method described in J. Het. Chem., 14(1), 129(1977) was followed to react 2-chloro-3-aminopyridine with potassium thiocyanate and hydrochloric acid in ethanol to produce 45.3 g of 2-aminothiazolo[5,4-b]pyridine. M+Theory 151; Found 151.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04692443 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-e0cd48ffacc248d99dbf02c05a61ca68 |
| Source note | uspto-grants-1987_09 |