Ethylenediamine → N-(2-Aminoethyl)-2-methylpropanamide

HRID 2308968Notes

Reaction equation

HRID 2308968 reaction equation
[CH2:1]([NH2:4])[CH2:2][NH2:3].[CH3:5][CH:6]([CH3:12])[C:7](OCC)=[O:8].NCC(N)(C)C>C(OCC)(=O)C>[CH3:5][CH:6]([CH3:12])[C:7]([NH:3][CH2:2][CH2:1][NH2:4])=[O:8]

Participants

5

Reactant 3

HCID 3301EthylenediamineHCID 7342Ethyl isobutyrateHCID 131282-Methylpropylenediamine

Product 1

HCID 12681828N-(2-Aminoethyl)-2-methylpropanamide

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The procedure of Example IX was repeated in all essential details to produce the above compound, except that equivalent amounts of ethylenediamine and ethyl 2,2-dimethylacetate were substituted for 1,2-diamino-2-methylpropane and ethyl acetate, respectively. The product, which was identified by NMR and IR spectroscopy, was recovered as an oil.

Workup

  1. customto produce the above compound
  2. customwas recovered as an oil

Sources & evidence

ORD record
ord-a26fdb4d4c2647c4bc6a97a76a6f4820
Source dataset
uspto-grants-1987_09
Patent number
US04692446

Reaction notes

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