反应详情

To a solution of the product from Example 81 (3.0 g.) in methanol (60 ml.), 1N sodium hydroxide (60 ml.) is added. After 4 hours, the solution is applied to a column of Dowex 50 ion exchange resin in the hydrogen cycle, and the desired material is eluted with water to yield 2.3 g. of the named product Rf 0.2 (silica gel-benzene:acetic acid, 75:25).

1. washthe desired material is eluted with water
2. customto yield 2.3 g