HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2309308Generated: November 2, 2026
Ethanolamine → 2-(3-Methylbutyl)-4,5-dihydro-1,3-oxazole
https://huagongshe.com/reaction/2309308
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | Pentanenitrile, 4-methyl- | HCID 10956 | — |
| Catalyst | Cadmium acetate, dihydrate | HCID 6537495 | — |
| Product | 2-(3-Methylbutyl)-4,5-dihydro-1,3-oxazole | HCID 20184955 | — |
Reaction Steps
A mixture of about 50.g grams (0.515 mole) isoamyl cyanide, about 31.5 grams (0.515 mole) ethanolamine, and about 3.2 grams (0.012 mole) cadmium acetate dihydrate is heated to about 115 degrees C. to about 125 degrees C. and stirred under nitrogen for about two days. The product is distilled under vacuum and the fraction boiling at about 81 degrees C. to about 84 degrees C. at about 29 mmHg is collected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04695295 |
|---|
| Source dataset | uspto-grants-1987_09 |
|---|
| ORD ID | ord-e1875b2239f744049f06eb7d48e32b16 |
|---|
| Source note | uspto-grants-1987_09 |
|---|
