HCID 3544471, compound → HCID 13672714, compound

HRID 2309351Notes

Reaction equation

HRID 2309351 reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[N+:13]([O-])=O)[CH:4]=[N:3]1>Cl>[CH3:1][N:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH2:13])[CH:4]=[N:3]1

Participants

3

Reactant 1

HCID 3544471HCID 3544471, compound

Product 1

HCID 13672714HCID 13672714, compoundYield 84.5%

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

By the procedure of Example 3, 25 g of 1-methyl-4-(2-nitrophenyl)-1H-pyrazole prepared in Example 17 was reacted with 81.2 g of stannous chloride dihydrate in 200 ml concentrated HCl at reflux for 1 hour to yield, after similar work up, 18 g of the title compound as an oil.

Workup

  1. temperatureat reflux for 1 hour
  2. customto yield

Sources & evidence

ORD record
ord-3c57cda69a344d0ca29777c688feb847
Source dataset
uspto-grants-1987_09
Patent number
US04695311

Reaction notes

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