HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetonitrile → HCID 20185087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetonitrile | HCID 7856 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Phenylpyrazolidin-3-one | HCID 269295 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 20185087 | HCID 20185087 | — |
Reaction Steps
In an analogous manner to the method described in Example 1B, 40 g 5-phenylpyrazolin-3-one in 120 ml dimethyl formamide were first deprotonated by reaction with 5.6 g of an 80% oily sodium hydride preparation and subsequently reacted with 11 ml chloroacetonitrile to form 3-cyanomethoxy-5-phenylpyrazole. Melting point: 143° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04695566 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-5799c1ccb44844c9a0d4670fc41356bc |
| Source note | uspto-grants-1987_09 |