Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2,3-Dihydro-1-benzofuran-5-amine | HCID 3841102 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | HCID 21864670 | HCID 21864670 | — |
Reaction Steps
A mixture of 148 g. (1.09 moles) of 5-amino-2,3-dihydrobenzofuran and 93 g. of W2 Raney nickel in 850 ml. of ethanol was heated to reflux for 24 hours. The reaction was cooled to 25° C., filtered and evaporated to give a quantitative yield of the desired intermediate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04695571 |
|---|
| Source dataset | uspto-grants-1987_09 |
|---|
| ORD ID | ord-cd6177102c7a472badc109a935ed793f |
|---|
| Source note | uspto-grants-1987_09 |
|---|
