反应详情

4.3 g of 2-(4-methoxy-3,5-dimethylphenyl)-3-methylindole and 13 g of pyridinium chloride were reacted at 200° C. for 1.5 hours. The reaction mixture was cooled, poured into water, extracted with ethyl acetate, washed with water, and dried. The solvent was evaporated, and the residue was recrystallized from benzene-hexane to give 2.6 g of 2-(4-hydroxy-3,5-dimethylphenyl)-3-methylindole.

1. temperatureThe reaction mixture was cooled
2. extractionextracted with ethyl acetate
3. washwashed with water
4. customdried
5. customThe solvent was evaporated
6. customthe residue was recrystallized from benzene-hexane