反应详情

2.8 g of 6-(2-methylphenyl)-2-methylpyridine was dissolved in 180 ml 1,4-dioxane, 1.4 g of selenium dioxide (Aldrich Gold Label) was added and the mixture refluxed for 36 hours. The solids were removed by filtration. Ether was added and the organic extracts washed five times with 100 ml water. After drying over magnesium sulfate and evaporation, 6-(2-methylphenyl)-2-pyridinecarboxaldehyde was afforded as a pale yellow oil (1.4 g).

1. temperaturethe mixture refluxed for 36 hours
2. customThe solids were removed by filtration
3. additionEther was added
4. washthe organic extracts washed five times with 100 ml water
5. dry with materialAfter drying over magnesium sulfate and evaporation