Hydrochloric Acid → HCID 13298050, compound

HRID 2309761Notes

Reaction equation

HRID 2309761 reaction equation
C([O:4][CH2:5][CH2:6][C:7]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[C:8]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=O)C.O.[OH-].[Na+].Cl>C(O)C>[C:15]1([C:8]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)=[C:7]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH2:6][CH2:5][OH:4])[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 13298049HCID 13298049, compound

Product 1

HCID 13298050HCID 13298050, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

34.2 g of 4-acetoxy-1,1,2-triphenyl-1-butene are dissolved in 200 ml of 94% ethanol, after which 20 ml of water and 45 ml of a 20% sodium hydroxide solution are added. The mixture is refluxed for 1 h. The solution is neutralized with 2M hydrochloric acid, after which the ethanol is evaporated. Water is added into the residue. The product is extracted in ethyl acetate, the ethyl acetate solution is dried over sodium sulfate and the solvent is evaporated. The product is recrystallized from a mixture of water and methanol and then has m.p. 117°-9° C. The yield is 23.7 g (79%).

Workup

  1. temperatureThe mixture is refluxed for 1 h
  2. customafter which the ethanol is evaporated
  3. additionWater is added into the residue
  4. extractionThe product is extracted in ethyl acetate
  5. dry with materialthe ethyl acetate solution is dried over sodium sulfate
  6. customthe solvent is evaporated
  7. customThe product is recrystallized from a mixture of water and methanol

Sources & evidence

ORD record
ord-3a09e36abbae44f2be50b3c77c6ceb8b
Source dataset
uspto-grants-1987_09
Patent number
US04696949

Reaction notes

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