Potassium Carbonate → HCID 54053038, compound

HRID 2309807Notes

Reaction equation

HRID 2309807 reaction equation
Cl.[CH3:2][CH:3]([N:6]1[C:10](=[O:11])[CH:9]([CH3:12])[S:8][C:7]1=[N:13][NH2:14])[CH:4]=[CH2:5].C(=O)([O-])[O-].[K+].[K+]>O>[CH3:2][CH:3]([N:6]1[C:10](=[O:11])[CH:9]([CH3:12])[S:8][C:7]1=[N:13][NH2:14])[CH:4]=[CH2:5]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 73664993HCID 73664993, compound

Product 1

HCID 54053038HCID 54053038, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To liberate the base, 52.4 g (0.222 Mol) of 3-(1-methylallyl)-5-methyl-2,4-thiazolidinedione-2-hydrazone hydrochloride is dissolved in 150 ml of water, and the solution saturated, with ice cooling and stirring, with potassium carbonate. The oil which precipitates is taken up in a mixture of 100 ml of methylene chloride and 100 ml of petroleum ether (B.P. 40°-60°), separated from the aqueous phase, and extracted by shaking with a solution of 25 g of potassium carbonate in 75 ml of water. The organic phase is separated, and concentrated in a water-jet vacuum to obtain 3-(1-methylallyl)-5-methyl-2,4-thiazolidinedione-2-hydrazone in the form of a colourless oil.

Workup

  1. customThe oil which precipitates
  2. additionis taken up in a mixture of 100 ml of methylene chloride and 100 ml of petroleum ether (B.P. 40°-60°)
  3. customseparated from the aqueous phase
  4. extractionextracted
  5. customThe organic phase is separated
  6. concentrationconcentrated in a water-jet vacuum

Sources & evidence

ORD record
ord-62a670841a4e4a308142a45aed98990b
Source dataset
uspto-grants-1987_09
Patent number
US04697020

Reaction notes

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