Ethyl Lactate → Ethyl 2-[(1'-ethoxy)propoxy]propanoate

HRID 2309808노트

반응식

HRID 2309808 반응식
[C:1]([O:6][CH2:7][CH3:8])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH:9]([O:12][CH2:13][CH3:14])=[CH:10][CH3:11]>Cl>[CH2:13]([O:12][CH:9]([O:3][CH:2]([CH3:4])[C:1]([O:6][CH2:7][CH3:8])=[O:5])[CH2:10][CH3:11])[CH3:14]

참가 물질

4

반응물 2

HCID 7344Ethyl LactateHCID 13570Ethyl 1-propenyl ether

생성물 1

HCID 21286133Ethyl 2-[(1'-ethoxy)propoxy]propanoate수율 90%

시약·촉매·용매 1

HCID 313Hydrochloric Acid촉매

반응 조건

온도
75 °C

실험 절차

To a 250 mL flask containing 37.0 g (0.31 mole) ethyl lactate and four drops 32% hydrochloric acid at 30° C. is added 71 g (0.82 mole) ethyl propenyl ether. The mixture is heated to 75° C. for thirty minutes, cooled to 25° C., then quenched with 100 g 5% sodium bicarbonate solution. The organic material was flash distilled yielding 52.3 g (90%) ethyl 2-[(1'-ethoxy)propoxy]propanoate.

후처리

  1. temperaturecooled to 25° C.
  2. customquenched with 100 g 5% sodium bicarbonate solution
  3. distillationdistilled

출처 및 근거

ORD 기록
ord-029abb63f1b0456b9a3dc9774107c98f
출처 데이터셋
uspto-grants-1987_09
특허 번호
US04697025

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