HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-Methoxy-4-(7H-purin-8-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Methoxy-4-(7H-purin-8-yl)benzonitrile | HCID 13284529 | — |
| Product | 3-Methoxy-4-(7H-purin-8-yl)benzamide | HCID 13284531 | — |
Reaction Steps
One gram of 8-(2'-methoxy-4'-cyano-phenyl)-purine was dissolved in 75 ml of 2N sodium hydroxide solution and refluxed for 15 minutes. Then, the mixture was acidified with hydrochloric acid, and the mixture precipitated was separated into its components by use of silica gel [eluant:methylene chloride/ethanol (7:3 to 1:1)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04696931 |
| Source dataset | uspto-grants-1987_09 |
| ORD ID | ord-46072a7ae601409092a8ae54ad079d8c |
| Source note | uspto-grants-1987_09 |