反应详情

An acetone solution of 90 m moles(21.8 g) of the above 4'-hydroxybiphenyl-4-carboxylic acid ethyl ester, 0.15 mole(49.2 g) of 1,12-dibromododecane, and 0.4 mole(55.3 g) of potassium carbonate was refluxed for four hours. The reaction sloution was filtered. The filtrate was concentrated, and then purified by column chromatography, to obtain 29.5 g of 4'-(12-bromododecyloxy)biphenyl-4-carboxylic acid ethyl ester [m.p. 88.6°-90.5° C⟧ (yield: 67%)

1. filtrationThe reaction sloution was filtered
2. concentrationThe filtrate was concentrated
3. custompurified by column chromatography