反应详情

An acetone solution of 90 m moles(21.8 g) of 4'-hydroxybiphenyl-4-carboxylic acid ethyl ester obtained in Example 24, 0.15 mole(57.6 g) of 1,16-dibromohexadecane, and 0.4 mole(55.3 g) of potassium carbonate was refluxed for four hours. The reaction solution was filtered. The filtrate was concentrated, and then purified by column chromatography to obtain 34.4 g of 4'-(16-bromohexadecyloxy)biphenyl-4-carboxylic acid ethyl ester. (yield: 70%)

1. filtrationThe reaction solution was filtered
2. concentrationThe filtrate was concentrated
3. custompurified by column chromatography