Dichloromethane → 3-(2-chloro-3-((4-(2-ethylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethoxy)-N-cyclopentyl-N-(2,2-dimethoxyethyl)propanamide

HRID 2310240Notes

Reaction equation

HRID 2310240 reaction equation
[CH3:46][O:47][CH:48]([CH2:49][NH:50][CH:51]1[CH2:52][CH2:53][CH2:54][CH2:55]1)[O:56][CH3:57].[CH:37]([N:38]([CH2:39][CH3:40])[CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[Cl:1][c:2]1[c:3]([CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9](=[O:10])[OH:11])[cH:12][cH:13][cH:14][c:15]1[CH2:16][N:17]1[CH2:18][CH2:19][C:20]2([CH2:21][N:22]([C:26](=[O:27])[c:28]3[n:29][c:30]([CH2:33][CH3:34])[s:31][cH:32]3)[CH2:23][CH2:24][O:25]2)[CH2:35][CH2:36]1.[Cl:82][CH2:83][Cl:84].[P-:58]([F:59])([F:60])([F:61])([F:62])([F:63])[F:64].[n:65]1([O:66][C:67]([N:68]([CH3:69])[CH3:70])=[N+:71]([CH3:72])[CH3:73])[c:74]2[n:75][cH:76][cH:77][cH:78][c:79]2[n:80][n:81]1>>[Cl:1][c:2]1[c:3]([CH2:4][CH2:5][O:6][CH2:7][CH2:8][C:9](=[O:11])[N:50]([CH2:49][CH:48]([O:47][CH3:46])[O:56][CH3:57])[CH:51]2[CH2:52][CH2:53][CH2:54][CH2:55]2)[cH:12][cH:13][cH:14][c:15]1[CH2:16][N:17]1[CH2:18][CH2:19][C:20]2([CH2:21][N:22]([C:26](=[O:27])[c:28]3[n:29][c:30]([CH2:33][CH3:34])[s:31][cH:32]3)[CH2:23][CH2:24][O:25]2)[CH2:35][CH2:36]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 581684923-(2-Chloro-3-((4-(2-ethylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethoxy)propanoic acidHCID 58168622N-(2,2-dimethoxyethyl)cyclopentanamine

Product 1

HCID 581684603-(2-chloro-3-((4-(2-ethylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)methyl)phenethoxy)-N-cyclopentyl-N-(2,2-dimethoxyethyl)propanamide

Sources & evidence

ORD record
ord-c1b6a42dea9742e781c01e93c7819e48
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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