反应详情

An acetone solution of 90 m moles(21.8 g) of 4-hydroxybiphenyl-4-carboxylic acid ethyl ester obtained in Example 24, 0.15 mole(45.0 g) of 1,10-dibromodecane, and 0.4 mole(55.3 g) of potassium carbonate was refluxed for four hours. The reaction solution was filtered. The filtrate was concentrated, and then purified by column chromatography, to obtain 29.9 g of 4'-(10-bromodecyloxy)biphenyl-4-carboxylic acid ethyl ester. (yield: 72%)

1. filtrationThe reaction solution was filtered
2. concentrationThe filtrate was concentrated
3. custompurified by column chromatography