Potassium Cation → tert-Butyl 4-(2-(2-chloroacetamido)ethyl)-4-hydroxypiperidine-1-carboxylate

HRID 2310263Notes

Reaction equation

HRID 2310263 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][CH2:30][O:31][C:32](=[O:33])[CH3:34].[Cl:1][CH2:2][C:3](=[O:4])[Cl:5].[K+:27].[K+:28].[NH2:6][CH2:7][CH2:8][C:9]1([OH:22])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[OH2:35]>>[Cl:1][CH2:2][C:3](=[O:4])[NH:6][CH2:7][CH2:8][C:9]1([OH:22])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6577Chloroacetyl chlorideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 45789931tert-Butyl 4-(2-aminoethyl)-4-hydroxypiperidine-1-carboxylate

Product 1

HCID 57989111tert-Butyl 4-(2-(2-chloroacetamido)ethyl)-4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-1aa5fc53abf54d5da3e4561f0db92f67
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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