反应详情

The compound from Step 4 (300 mg) was suspended in ethyl acetate (100 ml) and a solution of Na2S2O4 (2 g) in water (40 ml) was then added and the mixture was shaken until the orange-red coloration disappeared. The aqueous layer was decanted, the organic layer was washed with water, dried and evaporated to dryness. The resulting residue was treated with ether and filtered to afford the title compound (240 mg), m.p. 185° C.

1. customThe aqueous layer was decanted
2. washthe organic layer was washed with water
3. customdried
4. customevaporated to dryness
5. additionThe resulting residue was treated with ether
6. filtrationfiltered