Dichloromethane → Trifluoroacetic acid

HRID 2311171Notes

Reaction equation

HRID 2311171 reaction equation
[Cl:41][CH2:42][Cl:43].[F:1][C:2]([CH:3]([O:4][c:5]1[cH:6][n:7][cH:8][c:9]([N:11]2[CH2:12][CH:13]3[CH:14]([CH2:15]2)[CH2:16][N:17]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:18]3)[n:10]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)([F:32])[F:33].[F:34][C:35]([C:36](=[O:37])[OH:38])([F:39])[F:40]>>[F:1][C:2]([CH:3]([O:4][c:5]1[cH:6][n:7][cH:8][c:9]([N:11]2[CH2:12][CH:13]3[CH:14]([CH2:15]2)[CH2:16][NH:17][CH2:18]3)[n:10]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)([F:32])[F:33].[F:34][C:35]([C:36](=[O:37])[OH:38])([F:39])[F:40]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67265654Tert-butyl 2-[6-(2,2,2-trifluoro-1-phenylethoxy)pyrazin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Product 2

HCID 6422Trifluoroacetic acidHCID 178506349HCID 178506349, compound

Sources & evidence

ORD record
ord-257f41bbe77a4e118ac4cdae9bf0c0cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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