Water → 6-Bromo-2-(3-{[tert-butyl(dimethyl)silyl]oxy}-2,2-dimethylpropyl)isoquinolin-1(2H)-one
Reaction equation
[Br:21][c:22]1[cH:23][c:24]2[cH:25][cH:26][nH:27][c:28](=[O:32])[c:29]2[cH:30][cH:31]1.[Br:7][CH2:8][C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20].[C:1](=[O:2])([O-:3])[O-:4].[Cs+:5].[Cs+:6].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[OH2:38]>>[CH2:8]([C:9]([CH2:10][O:11][Si:12]([CH3:13])([CH3:14])[C:15]([CH3:16])([CH3:17])[CH3:18])([CH3:19])[CH3:20])[n:27]1[cH:26][cH:25][c:24]2[cH:23][c:22]([Br:21])[cH:31][cH:30][c:29]2[c:28]1=[O:32]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-32f1b79a86654f2d8b026ebd22795006
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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