反应详情

To a solution of 9.97 g of 4-methoxybenzenesulfonamide in 54 ml of acetone were added 54 ml of a 1N sodium hydroxide solution. With stirring, a solution of 11.55 g of 4-bromophenylisocyanate in 50 ml of acetone was added. After stirring at room temperature for three days, the reaction mixture was filtered and 55 ml of 1N hydrochloric acid were added to the filtrate providing a fine white precipitate. Two hundred milliliters of water were added, and the solid was recovered by filtration to provide 18.85 g of the desired title product.

1. stirringAfter stirring at room temperature for three days
2. filtrationthe reaction mixture was filtered
3. addition55 ml of 1N hydrochloric acid were added to the filtrate
4. customproviding a fine white precipitate
5. filtrationthe solid was recovered by filtration