Hydrochloric Acid → 3-(5-Phenyl-1,2,4-oxadiazol-3-yl)-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazin-2-amine

HRID 2311852Notes

Reaction equation

HRID 2311852 reaction equation
[CH3:39][OH:40].[ClH:1].[NH2:8][c:9]1[n:10][cH:11][c:12]([C:26]2=[CH:31][CH2:30][N:29]([C:32]([O:33][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38])[CH2:28][CH2:27]2)[n:13][c:14]1-[c:15]1[n:16][o:17][c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[n:19]1.[O:2]1[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1>>[NH2:8][c:9]1[n:10][cH:11][c:12]([C:26]2=[CH:31][CH2:30][NH:29][CH2:28][CH2:27]2)[n:13][c:14]1-[c:15]1[n:16][o:17][c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[n:19]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 66744707tert-butyl 4-(5-amino-6-(5-phenyl-1,2,4-oxadiazol-3-yl)pyrazin-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 667444423-(5-Phenyl-1,2,4-oxadiazol-3-yl)-5-(1,2,3,6-tetrahydropyridin-4-yl)pyrazin-2-amine

Sources & evidence

ORD record
ord-526141af60af49f69d964a4b4cbac5c7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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