Sodium ion → (Z)-8-bromo-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one

HRID 2311869Notes

Reaction equation

HRID 2311869 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[NH:7][C:8](=[O:18])[CH2:9][N:10]=[C:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[CH3:22][I:23].[H-:20].[Na+:21].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:19]1)[N:7]([CH3:22])[C:8](=[O:18])[CH2:9][N:10]=[C:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 166653HydrideHCID 59783468(Z)-8-bromo-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Product 1

HCID 59783784(Z)-8-bromo-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one

Sources & evidence

ORD record
ord-c04a8ad8710842f0b50787ac19454ffb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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