Ammonia → 4-Chloro-8-(difluoromethoxy)quinoline
Reaction equation
[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[c:9]([OH:14])[cH:10][cH:11][n:12][c:13]12)[F:15].[NH3:16].[P:17]([Cl:18])([Cl:19])([Cl:20])=[O:21]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][cH:7][c:8]2[c:9]([Cl:19])[cH:10][cH:11][n:12][c:13]12)[F:15]Participants
4
Sources & evidence
- ORD record
- ord-556b7ca9ae6f477d8c060f9717559a54
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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