Dichloromethane → 6-[4-(5-Fluoro-2-trifluoromethylbenzoyl)piperazin-1-YL]imidazo[1,2-B]pyridazine-2-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7][c:8]2[n:9]([n:10][c:11]([N:14]3[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]3)[cH:12][cH:13]2)[cH:20]1.[CH:21]([N:22]([CH:23]([CH3:24])[CH3:25])[CH2:26][CH3:27])([CH3:28])[CH3:29].[Cl:44][CH2:45][Cl:46].[F:30][c:31]1[cH:32][cH:33][c:34]([C:40]([F:41])([F:42])[F:43])[c:35]([C:36](=[O:37])[Cl:38])[cH:39]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[n:7][c:8]2[n:9]([n:10][c:11]([N:14]3[CH2:15][CH2:16][N:17]([C:36]([c:35]4[c:34]([C:40]([F:41])([F:42])[F:43])[cH:33][cH:32][c:31]([F:30])[cH:39]4)=[O:37])[CH2:18][CH2:19]3)[cH:12][cH:13]2)[cH:20]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-574d5493810a44248187b838e7a08bd9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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