Dimethyl Sulfoxide → trans-4-(5-Chloro-4-iodopyridin-2-yl-amino)cyclohexanol

HRID 2312358Notes

Reaction equation

HRID 2312358 reaction equation
[CH3:10][S:11]([CH3:12])=[O:13].[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[Cl:1][c:2]1[c:3]([I:9])[cH:4][c:5]([F:8])[n:6][cH:7]1.[NH2:14][CH:15]1[CH2:16][CH2:17][CH:18]([OH:21])[CH2:19][CH2:20]1>>[Cl:1][c:2]1[c:3]([I:9])[cH:4][c:5]([NH:14][CH:15]2[CH2:16][CH2:17][CH:18]([OH:21])[CH2:19][CH2:20]2)[n:6][cH:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 8857Ethyl AcetateHCID 812934-AminocyclohexanolHCID 218653365-Chloro-2-fluoro-4-iodopyridine

Product 1

HCID 66937023trans-4-(5-Chloro-4-iodopyridin-2-yl-amino)cyclohexanol

Sources & evidence

ORD record
ord-02ae7a1ea03c4967849125e27bff2de6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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