Ammonia → [(2-Aminoethoxy)(3-hydroxyphenyl)methylene]adamantane

HRID 2312513Notes

Reaction equation

HRID 2312513 reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[NH3:23].[OH:1][c:2]1[cH:3][c:4]([C:8]([O:9][CH2:10][CH2:11][I:12])=[C:13]2[CH:14]3[CH2:15][CH:16]4[CH2:17][CH:18]([CH2:19][CH:20]2[CH2:21]4)[CH2:22]3)[cH:5][cH:6][cH:7]1>>[OH:1][c:2]1[cH:3][c:4]([C:8]([O:9][CH2:10][CH2:11][NH2:23])=[C:13]2[CH:14]3[CH2:15][CH:16]4[CH2:17][CH:18]([CH2:19][CH:20]2[CH2:21]4)[CH2:22]3)[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 8028TetrahydrofuranHCID 15158795[(3-Hydroxyphenyl)(2-iodoethoxy)methylene]adamantane

Product 1

HCID 15158796[(2-Aminoethoxy)(3-hydroxyphenyl)methylene]adamantane

Sources & evidence

ORD record
ord-f5f7db43f54f46aa8fe58872651d718b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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