Sodium ion → (1-(4-(Azetidin-3-yloxy)-2-methylbenzyl)-4-methylpiperidin-4-yl)methanol

HRID 2312525Notes

Reaction equation

HRID 2312525 reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[Cl:44][CH2:45][Cl:46].[F:30][C:31]([F:32])([F:33])[C:34]([OH:35])=[O:36].[Na+:42].[Na+:43].[OH2:37].[OH:1][CH2:2][C:3]1([CH3:29])[CH2:4][CH2:5][N:6]([CH2:9][c:10]2[c:11]([CH3:28])[cH:12][c:13]([O:14][CH:15]3[CH2:16][N:17]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:18]3)[cH:26][cH:27]2)[CH2:7][CH2:8]1>>[OH:1][CH2:2][C:3]1([CH3:29])[CH2:4][CH2:5][N:6]([CH2:9][c:10]2[c:11]([CH3:28])[cH:12][c:13]([O:14][CH:15]3[CH2:16][NH:17][CH2:18]3)[cH:26][cH:27]2)[CH2:7][CH2:8]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 19660Carbonate IonHCID 58043112HCID 58043112, compound

Product 1

HCID 66656363(1-(4-(Azetidin-3-yloxy)-2-methylbenzyl)-4-methylpiperidin-4-yl)methanol

Sources & evidence

ORD record
ord-836264ca002d4d3aa3f5646899b439b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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