反应详情

To 120 ml of dichloromethane are added 12.0 g of 2-methoxy-3-octadecyloxypropanol and 6.07 ml of triethylamine, to which 4.98 g of methanesulfonyl chloride is added dropwise with stirring under ice cooling. Thereafter, the mixture is stirred at room temperature for 2 hours to complete the reaction. The reaction mixture is then washed with water, an aqueous sodium bicarbonate solution and again water and dried over anhydrous sodium sulfate. The solvent is distilled off under reduced pressure to leave 14.6 g (100%) of the captioned compound.

1. stirringThereafter, the mixture is stirred at room temperature for 2 hours
2. customthe reaction
3. washThe reaction mixture is then washed with water
4. dry with materialan aqueous sodium bicarbonate solution and again water and dried over anhydrous sodium sulfate
5. distillationThe solvent is distilled off under reduced pressure