Trimethylamine → HCID 14498244, compound

HRID 231261Notes

Reaction equation

HRID 231261 reaction equation
[S:1]([O-:5])(=[O:4])(=[O:3])[CH3:2].[OH:6][CH:7]([CH2:19][O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:8][S:9]([CH2:12][CH2:13][CH2:14][N+:15]([CH3:18])([CH3:17])[CH3:16])(=[O:11])=[O:10].[CH3:39][N:40]=[C:41]=[O:42].CN(C)C>C(Cl)(Cl)Cl>[S:1]([O-:5])(=[O:4])(=[O:3])[CH3:2].[CH3:39][NH:40][C:41]([O:6][CH:7]([CH2:19][O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:8][S:9]([CH2:12][CH2:13][CH2:14][N+:15]([CH3:17])([CH3:16])[CH3:18])(=[O:11])=[O:10])=[O:42]

Participants

5

Reactant 3

HCID 1146TrimethylamineHCID 12228Methyl IsocyanateHCID 14498242HCID 14498242, compound

Product 1

HCID 14498244HCID 14498244, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Into 6 ml of chloroform are added 1.4 g of 3-[(2-hydroxy-3-octadecyloxypropyl)sulfonyl]propyltrimethylammonium mesylate, 1 ml of methyl isocyanate and 1 ml of trimethylamine and the mixture is shaked overnight at room temperature. The reaction mixture is concentrated under reduced pressure and the residue is purified by silica gel column chromatography to give 0.2 of the captioned

Workup

  1. concentrationThe reaction mixture is concentrated under reduced pressure
  2. customthe residue is purified by silica gel column chromatography
  3. customto give 0.2 of the

Sources & evidence

ORD record
ord-6e2df9b3dabc46adb704c65bace0ce45
Source dataset
uspto-grants-1989_07
Patent number
US04845219

Reaction notes

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