2-Chloro-5-fluoropyrimidin-4-amine → Hydrochloric Acid

HRID 2312649Notes

Reaction equation

HRID 2312649 reaction equation
[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][C:9]23[c:10]4[cH:11][cH:12][cH:13][cH:14][c:15]4[CH:16]([c:17]4[cH:18][cH:19][cH:20][cH:21][c:22]42)[CH2:23]3)[CH2:6][CH2:7]1.[NH2:24][c:25]1[n:26][c:27]([Cl:32])[n:28][cH:29][c:30]1[F:31]>>[ClH:32].[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][C:9]23[c:10]4[cH:11][cH:12][cH:13][cH:14][c:15]4[CH:16]([c:17]4[cH:18][cH:19][cH:20][cH:21][c:22]42)[CH2:23]3)[CH2:6][CH2:7]1)[c:27]1[n:26][c:25]([NH2:24])[c:30]([F:31])[cH:29][n:28]1

Participants

4

Reactant 2

HCID 2543722-Chloro-5-fluoropyrimidin-4-amineHCID 193810314-Amino-1-(9,10-dihydro-9,10-methanoanthracen-9-ylmethyl)piperidine

Product 2

HCID 313Hydrochloric AcidHCID 541281134-Amino-2-[1-(9,10-dihydro-9,10-methanoanthracen-9-ylmethyl)-4-piperidylamino]-5-fluoropyrimidine

Sources & evidence

ORD record
ord-93a9ab13da304d80b8d0aae6957b6ef2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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