反应详情

In 100 ml of dichloromethane are dissolved 8.9 g of 2-methoxy-3-(12-cyclohexyldodecyloxy)propyl 3-hydroxypropyl sulfone and 3.7 ml of triethylamine, to which 3.0 g of methanesulfonyl chloride is added dropwise with stirring under ice cooling. After 2 hours stirring at room temperature, the reaction solution is washed with water, an aqueous sodium bicarbonate solution and water, and dried. The solvent is then distilled off under reduced pressure to leave 10.4 g of the captioned compound.

1. stirringAfter 2 hours stirring at room temperature
2. washthe reaction solution is washed with water
3. dry with materialan aqueous sodium bicarbonate solution and water, and dried
4. distillationThe solvent is then distilled off under reduced pressure