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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2312969Generated: October 30, 2026

6-Chloro-2-methylnicotinonitrile → 2-[(5-Cyano-6-methylpyridin-2-yl)amino]-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

https://huagongshe.com/reaction/2312969

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-2-methylnicotinonitrileHCID 12387737—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product2-[(5-Cyano-6-methylpyridin-2-yl)amino]-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525677—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-6baacde0bd68440c91b5fd070a4735cb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)