Hydrochloric Acid → tert-butyl 1-((5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)methylcarbamothioyl)pyrrolidin-3-ylcarbamate
Reaction equation
[C:23](=[S:24])([n:25]1[cH:26][cH:27][n:28][cH:29]1)[n:30]1[cH:31][cH:32][n:33][cH:34]1.[Cl:53][CH2:54][Cl:55].[ClH:1].[NH:35]1[CH2:36][CH:37]([NH:40][C:41]([O:42][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:47])[CH2:38][CH2:39]1.[Na+:52].[O-:48][C:49]([OH:50])=[O:51].[S:2](=[O:3])(=[O:4])([c:5]1[cH:6][cH:7][c:8]([CH3:9])[cH:10][cH:11]1)[n:12]1[cH:13][cH:14][c:15]2[c:16]1[n:17][cH:18][c:19]([CH2:21][NH2:22])[n:20]2>>[S:2](=[O:3])(=[O:4])([c:5]1[cH:6][cH:7][c:8]([CH3:9])[cH:10][cH:11]1)[n:12]1[cH:13][cH:14][c:15]2[c:16]1[n:17][cH:18][c:19]([CH2:21][NH:22][C:23](=[S:24])[N:35]1[CH2:36][CH:37]([NH:40][C:41]([O:42][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:47])[CH2:38][CH2:39]1)[n:20]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-88f7535d16d648b486379ee5388aec1b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…