1-Butanol → 1-benzhydrylazetidine

HRID 2313270Notes

Reaction equation

HRID 2313270 reaction equation
[Br:12][CH2:13][CH2:14][CH2:15][Cl:16].[C:1](=[O:2])([O-:3])[O-:4].[CH2:7]([CH2:8][CH2:9][CH3:11])[OH:10].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[CH:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[NH2:30].[K+:5].[K+:6].[OH2:31]>>[CH2:7]1[CH2:8][CH2:9][N:30]1[CH:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1

Participants

8

Reactant 7

HCID 2631-ButanolHCID 813Potassium Cation2×HCID 962WaterHCID 1140TolueneHCID 7036BenzhydrylamineHCID 80061-Bromo-3-chloropropaneHCID 19660Carbonate Ion

Product 1

HCID 28028951-benzhydrylazetidine

Sources & evidence

ORD record
ord-44b1efc846374f6589abbc5a802c46fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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