Bromine → 1-Bromo-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one

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Reaction Steps

Thus, for example, 3,3-dimethyl-1-(4-methoximinomethyl-phenoxy)-1-(1,2,4-triazol-1-yl)-butan-2-one of the formula ##STR11## can be prepared by reacting 3,3-dimenthyl-1-(1,2,4-triazol-1-yl)-butan-2-one initially with bromine to form 1-bromo-(1,2,4-triazol-1-yl)-3,3-dimethyl-butan-2-one, and subsequently reaching this with 4-hydroxybenzaldehyde O-methyl oxime ether in the presence of a base. This synthesis can be illustrated by means of formulae as follows:

Provenance & Evidence