Ethanolamine → 2-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

HRID 231374Notes

Reaction equation

HRID 231374 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4](Cl)[C:3]=1[N+:10]([O-:12])=[O:11].[CH2:13]([CH2:15][NH2:16])[OH:14]>>[Cl:8][C:6]1[CH:5]=[C:4]([NH:16][CH2:15][CH2:13][OH:14])[C:3]([N+:10]([O-:12])=[O:11])=[C:2]([NH:16][CH2:15][CH2:13][OH:14])[CH:7]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 292282,4,6-Trichloronitrobenzene

Product 1

HCID 200710912-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

Procedure

0.132 mole (30 g) of 2,4,6-trichloronitrobenzene is heated to 95° C. in 120 ml of ethanolamine. After 30 minutes, the reaction medium is poured into 240 g of an ice-water mixture. The product expected precipitates. It is drained, washed with water and then dried under vacuum in the presence of phosphorous pentoxide. After recrystallizing from absolute ethanol, it melts at 154° C.

Workup

  1. customThe product expected precipitates
  2. washwashed with water
  3. dry with materialdried under vacuum in the presence of phosphorous pentoxide
  4. customAfter recrystallizing from absolute ethanol, it melts at 154° C.

Sources & evidence

ORD record
ord-0b6c28dde6634d2b8761689383ed485d
Source dataset
uspto-grants-1989_07
Patent number
US04845293

Reaction notes

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