Ethanolamine → 2-(beta-Hydroxyethyl)amino-6-(beta-hydroxyethyl)amino-4-chloronitrobenzene

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Reaction Steps

0.132 mole (30 g) of 2,4,6-trichloronitrobenzene is heated to 95° C. in 120 ml of ethanolamine. After 30 minutes, the reaction medium is poured into 240 g of an ice-water mixture. The product expected precipitates. It is drained, washed with water and then dried under vacuum in the presence of phosphorous pentoxide. After recrystallizing from absolute ethanol, it melts at 154° C.

Provenance & Evidence