HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloro-2-nitrobenzene → 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloro-2-nitrobenzene | HCID 11759 | — |
| Reactant | 3-Amino-1,2-propanediol | HCID 73561 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene | HCID 20035240 | — |
Reaction Steps
0.2 mole (38.4 g) of 2,6-dichloronitrobenzene and 0.6 mole (54.6 g) of 3-aminopropane-1,2-diol in 200 ml of 1-methyl-2-pyrrolidone are heated to 80° C. The reaction mixture is diluted with ice. The product expected precipitates. After recrystallizing from isopropanol, it melts at 126° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04845293 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-15b4c36b60604eb984e0b22c2aa363ea |
| Source note | uspto-grants-1989_07 |