Dichloromethane → N-benzyl-2-(4-benzylbenzamido)-4-methylthiazole-5-carboxamide

HRID 2314272Notes

Reaction equation

HRID 2314272 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:17])[n:13][c:14]([NH2:16])[s:15]1.[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[c:34]1[cH:35][cH:36][c:37]([C:38](=[O:39])[OH:40])[cH:41][cH:42]1.[CH3:50][N+:51]([CH3:52])=[C:53]([N:54]([CH3:55])[CH3:56])[O:57][n:58]1[c:59]2[n:60][cH:61][cH:62][cH:63][c:64]2[n:65][n:66]1.[CH:18]([N:19]([CH:20]([CH3:21])[CH3:22])[CH2:23][CH3:24])([CH3:25])[CH3:26].[Cl:67][CH2:68][Cl:69].[F:43][P-:44]([F:45])([F:46])([F:47])([F:48])[F:49]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][C:9](=[O:10])[c:11]1[c:12]([CH3:17])[n:13][c:14]([NH:16][C:38]([c:37]2[cH:36][cH:35][c:34]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[cH:42][cH:41]2)=[O:39])[s:15]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 1364294-Benzylbenzoic acidHCID 210824N-Benzyl-2-imino-4-methyl-2,3-dihydro-1,3-thiazole-5-carboximidic acidHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium

Product 1

HCID 59369673N-benzyl-2-(4-benzylbenzamido)-4-methylthiazole-5-carboxamide

Sources & evidence

ORD record
ord-a2641818bc6240bca6c343f1539d6fa8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…