HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium ethoxide → 2-Bromo-1-(ethoxymethyl)-4-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | 2-Bromo-1-(bromomethyl)-4-fluorobenzene | HCID 10706977 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Bromo-1-(ethoxymethyl)-4-fluorobenzene | HCID 20032356 | — |
Reaction Steps
By the method of Example 1, Step A, 10.9 g (0.041 mole) of 2-bromo-4-fluorobenzyl bromide and 18.2 ml of a 21% by weight solution of sodium ethoxide in ethanol were reacted in 50 ml of tetrahydrofuran, yielding 7.18 g of ethyl 2-bromo-4-fluorobenzyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04846882 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-c50c1de3d01844b7ba0c5d3980a95b3f |
| Source note | uspto-grants-1989_07 |